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Product Serum

Experience a serum that helps provide youth-restoring firmness, volume and lift.

Helps the jawline area appear lifted.
Helps define and perfect facial contours.
Firms and tightens sagging skin.
Helps reverse loss of cushion.
Provides lifting that lasts throughout the day.

NEW! TimeWise Plus+™
Regena-Firm™ Intensive Serum

Women love TimeWise+™ Regena-Firm™ Intensive Serum!*

During a four-week independent consumer study, a majority of women agreed that this lightweight serum felt luxurious, reduced the look of crepiness in the neck area, transformed the appearance of skin texture and helped skin look years younger. Here's what else they said:

AFTER 1 WEEK:*	AFTER 2 WEEKS:*	AFTER 4 WEEKS:*
80% Helps provide a noticeable lifting sensation	78% Helps the jawline area appear lifted	82% Provides lifting that lasts throughout the day
88% Helps replenish skin moisture:	81% Helps define and perfect facial contours	79% Neck area looks firmed
	82% Firms and tightens sagging skin
	79% Helps reverse the loss of cushion

Here's the science behind TimeWise Plus+™ Regena-Firm™ Intensive Serum:

It's designed to promote skin resilience and influence production of Laminin-5. Learn more.
It helps replenish vital hydration.** Learn more.
It contains a powerful botanical that minimizes the activity of matrix-degrading enzymes.** Learn more.
It contains the TimeWise Plus+™ Regena-Firm™ Complex.

Price is suggested retail
* Results based on a four-week independent consumer study. The percentage reflects the number of women who agreed with the statement.

**Based on in-vitro testing of key ingredients

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Laminins are part of a family of glycoproteins found near the dermal-epidermal junction (DEJ), an area of the skin that plays a critical role in cellular communication and nutrient exchange.
In younger skin, the wavy, fingerlike projections of the DEJ allow nutrients to flow from one layer to another. As skin ages, these "waves" begin to flatten. This makes the skin more fragile, decreasing the amount of nutrients available to the epidermis and interfering with the skin's normal repair process. This flattening of the DEJ can cause skin to wrinkle and sag.
Laminins play an important role in the skin because they influence cell differentiation, migration and adhesion, and are considered vital to the structural "scaffolding" of the skin.
Laminin-5 is considered an anchoring glycoprotein capable of binding to skin cells, which helps strengthen the connection and provide support between the layers of skin.
TimeWise Plus+™ Regena-Firm™ Intensive Serum is designed to promote skin resilience by influencing the production of Laminin-5 and helping minimize damage to proteins near the DEJ.

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Moisturization plays a crucial role in skin health. For skin to stay healthy, water must be able to move within the skin. That's where aquaporins come in.
Aquaporins are skin proteins that create channels that help water travel to where it's needed the most, helping with skin hydration. A type of these proteins – called AQP3 – transports not only water but glycerol, which has moisture-binding properties.
Glycerol in skin is also critical because it is known to help strengthen the skin barrier and prevent moisture loss through evaporation. (Think of it as "waterproofing" for your skin.) AQP3 channels in the skin are negatively impacted by age and cumulative exposure to sun and other elements, and this is believed to contribute to the dryness associated with older skin.
TimeWise Plus+™ Regena-Firm™ Intensive Serum is formulated with a marine botanical that has been shown to help replenish water channels critical to sustain skin's moisture levels.

*Based on in-vitro testing of key ingredients

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Throughout our lives, the skin is in a constant state of degradation and renewal, a process that is kept in optimal balance when we are younger.
As we age, however, chronological and environmental factors overwhelm the skin and the dermal matrix begins to degrade faster than it can be renewed.
Increased activity of MMPs (matrix metalloproteinases) is a common problem in older skin, and left unchecked, it can contribute to the destruction of skin proteins faster than these proteins can be replaced.
TimeWise Plus+™ Regena-Firm™ Intensive Serum is formulated with a botanical extract that reduces the activity of MMPs.* Ingredient: Argan Seed Extract

*Based on in-vitro testing of key ingredients

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The skin around the eyes has an extremely low concentration of oil glands that leaves it particularly vulnerable to crepiness and drying.
Cumulative UV exposure and the reduction in hyaluronic acid production that happens with age can aggravate the issue.
TimeWise Plus+™ Regena-Firm™ Correcting Eye Cream contains ingredients shown to help renew hyaluronic acid,* and help provide long-term hydration. Ingredients: Centella Asiatica Extract, Esters Derived From Olive Oil, Glycerin and Emollients.

*Based on in-vitro testing of key ingredients