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The Regena-Firm™ Complex, the result of sophisticated biotechnology and unprecedented innovation, delivers three vital ingredients:
- Plant stem cells that help protect the integrity of the skin matrix, the source of skin firmness.
- Tripeptide 1, a biomimetic peptide that helps support processes critical for skin repair.
- Botanicals that are shown to boost the production of hyaluronic acid,* helping to provide youthful volume and lift.
* Based on in-vitro testing of key ingredients.
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*Based on in-vitro testing of key ingredients
The Power of Plant Stem Cells
Skin is constantly renewing itself as older skin cells die and are replaced. But as time passes, the old cells begin to outnumber and overwhelm the new, and this declining ability of skin to renew itself plays a big role in the advanced signs of aging ultimately becoming visible. Now the Regena-Firm™ Complex harnesses the power of plant stem cells to help maintain skin integrity.*
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The Benefits of Plant Stem Cells
- The plant stem cells in TimeWise Plus+™ Skin Care come from gotu kola, a potent botanical known for its antioxidant properties.
- This ingredient is prized because it can reduce the activity of hyaluronidase,* a skin matrix-degrading enzyme that can lead to a loss of skin firmness.
- Minimizing the activity of hyaluronidase is critical since it breaks down hyaluronic acid, a key component that acts as a "space filler" within the dermal matrix and is responsible for hydration and providing a volumizing effect in addition to impacting skin elasticity.
- This highly prized benefit to skin can't be overemphasized – since promoting the production of hyaluronic acid in skin without keeping current levels from degrading would be like filling a bathtub without putting a plug in the drain. The good news is that the Regena-Firm™ Complex was designed to support both.
Did you know?
In contrast to human stem cells, plant stem cells have the ability to regenerate an entirely new plant. Plant stem cells never undergo the aging process but instead can eternally give rise to new cells that have the potential to grow into any tissue. Plant stem cells have the unique capacity to energize and protect cells.
*Based on in-vitro testing of key ingredients
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The Importance of Hyaluronic Acid (HA)
While the best-known components of the skin matrix are the structural proteins collagen and elastin, hyaluronic acid (HA) performs an equally vital role, providing essential cushioning and holding onto moisture that can actually plump skin from within.
What is HA?
HA and Aging
*Based on in-vitro testing of key ingredients
The Importance of Hyaluronic Acid (HA)
While the best-known components of the skin matrix are the structural proteins collagen and elastin, hyaluronic acid (HA) performs an equally vital role, providing essential cushioning and holding onto moisture that can actually plump skin from within.
The Dermal Matrix
Think of the dermal matrix as skin’s foundation – just like steel beams provide the framework of a building – while hyaluronic acid provides the “padding,” filling in the empty spaces. Hyaluronic acid is to skin what water is to a sponge – without it skin can become extremely dehydrated, leading to wrinkled, sagging, less-elastic skin.
What is HA?
- Hyaluronic acid is a glycosaminoglycan, or GAG, which is a combination of proteins and sugars found in a variety of tissues and located primarily on the surface of cells or in the skin matrix.
- While hyaluronic acid occurs naturally throughout the body, over 50 percent of the total amount is found in the skin.
- Because of its natural ability to bind up to 1,000 times its weight in water, hyaluronic acid is the most important GAG when it comes to providing benefits to the skin. In fact, many experts agree that as far as skin rejuvenation is concerned, hyaluronic acid plays a starring role.
HA and Aging
- Like so many other things, the amount of HA in skin decreases with age, accelerating more rapidly in the late 40s – early 50s. The most dramatic loss of hyaluronic acid associated with aging skin is in the epidermis.
- This natural process robs skin of its youthful suppleness and allows deeper wrinkles and other advanced signs of skin aging to appear. This loss can be compounded further by environmental factors, nutrition and lifestyle habits.
- When hyaluronic acid is diminished, skin cannot retain the water it needs at the cellular level to keep the underlying structure of the skin hydrated and healthy.
- Optimal levels of hyaluronic acid help provide the nutrient-transporting framework your skin needs to survive. The Regena-Firm™ Complex contains hyaluronic acid-boosting botanicals* that can help replenish skin volume and the natural-looking “cushion” associated with younger skin.
Did you know?
There are two ways that hyaluronic acid can be added to skin.
1. One way is by adding it to a product formula and applying it topically so it can sit on skin and attract vital moisture.
2. The second way is how the Regena-Firm™ Complex delivers it – by helping to promote the production of hyaluronic acid* so skin is not only able to attract and collect moisture, but also to hold onto it. This can help boost skin volume and create a plumping effect.
There are two ways that hyaluronic acid can be added to skin.
1. One way is by adding it to a product formula and applying it topically so it can sit on skin and attract vital moisture.
2. The second way is how the Regena-Firm™ Complex delivers it – by helping to promote the production of hyaluronic acid* so skin is not only able to attract and collect moisture, but also to hold onto it. This can help boost skin volume and create a plumping effect.
*Based on in-vitro testing of key ingredients
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The Power of the Peptide
This specialized peptide “mimics” skin factors which can influence skin behaviors. It is structurally similar to skin-signaling proteins that tell healthy skin to do what it already knows how to do – like make more proteins or communicate with one another. Strong cell communication is fundamental to skin health, since when cells stop “talking” to each other, normal skin function can become impaired.
The Dermal-Epidermal Junction (DEJ)
How the DEJ Works
The Regena-Firm™ Complex contains Tripeptide 1 to promote the synthesis of skin proteins* that help maintain skin integrity and promote cellular communication.
*Based on in-vitro testing of key ingredients
The Power of the Peptide
This specialized peptide “mimics” skin factors which can influence skin behaviors. It is structurally similar to skin-signaling proteins that tell healthy skin to do what it already knows how to do – like make more proteins or communicate with one another. Strong cell communication is fundamental to skin health, since when cells stop “talking” to each other, normal skin function can become impaired.
The Dermal-Epidermal Junction (DEJ)
- This peptide also promotes the synthesis of two proteins in skin* that are critical to its strength and support – fibronectin and laminin. Unlike collagen and elastin, proteins that can appear throughout the dermis, fibronectin and laminin are localized primarily in the area of the skin known as the dermal-epidermal junction (DEJ) which is where the epidermis connects to the dermis.
- While collagen and elastin perform a structural role in the skin, fibronectin and laminin primarily influence the communication of cells in the DEJ as well as cellular adhesion – the process through which cells physically bind together and to the DEJ. These two processes are essential if skin is to function properly.
How the DEJ Works
- In younger skin, the fingerlike projections of the DEJ – imagine a wavy line – allow nutrients to flow from one layer to another. As skin ages, these "waves" begin to flatten. This makes the skin more fragile, decreasing the amount of nutrients available to the epidermis and interfering with the skin's normal repair process.
- This flattening of the DEJ can cause skin to wrinkle and sag, so anything that can be done to support this area is a good thing for aging skin.
- Here’s an easy way to visualize what’s going on. Think of the dermis as a tripod, and each of the legs represents one of the three elements essential to healthy, young-looking skin – collagen, elastin and hyaluronic acid.
- Now imagine that hinges attach the legs to one another across the bottom. Just as those hinges connect the legs, fibronectin and laminin work to bind and connect other proteins and strengthen the skin’s network of support.
The Regena-Firm™ Complex contains Tripeptide 1 to promote the synthesis of skin proteins* that help maintain skin integrity and promote cellular communication.
Did you know?
Improved cellular communication can lead to enhanced cellular repair, helping to slow the appearance of the advanced signs of aging – like deepening lines, wrinkles and sagging skin – by strengthening the biomechanical properties of the skin.
Improved cellular communication can lead to enhanced cellular repair, helping to slow the appearance of the advanced signs of aging – like deepening lines, wrinkles and sagging skin – by strengthening the biomechanical properties of the skin.
*Based on in-vitro testing of key ingredients
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*Based on in-vitro testing of key ingredients
- The skin around the eyes has an extremely low concentration of oil glands that leaves it particularly vulnerable to crepiness and drying.
- Cumulative UV exposure and the reduction in hyaluronic acid production that happens with age can aggravate the issue.
- TimeWise Plus+™ Regena-Firm™ Correcting Eye Cream contains ingredients shown to help renew hyaluronic acid,* and help provide long-term hydration. Ingredients: Centella Asiatica Extract, Esters Derived From Olive Oil, Glycerin and Emollients.
*Based on in-vitro testing of key ingredients
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